Bewegungsstörungen im Kindes-alter und ihre Differenzialdiagnose zur Epilepsie/zum epileptischen Anfall

G. Kurlemann; B. Fiedler

doi:10.1055/s-0038-1629307

Kinder- und Jugendmedizin, Inhaltsverzeichnis

Kinder- und Jugendmedizin 2012; 12(06): 347-355
DOI: 10.1055/s-0038-1629307

Neuropädiatrie

Schattauer GmbH

Bewegungsstörungen im Kindes-alter und ihre Differenzialdiagnose zur Epilepsie/zum epileptischen Anfall

Movement disorders in childhood and their differential diagnosis to epilepsy/epileptic seizures

G. Kurlemann

¹Klinik für Kinder- und Jugendmedizin, Universitäts-Kinderklink Münster

,

B. Fiedler

¹Klinik für Kinder- und Jugendmedizin, Universitäts-Kinderklink Münster

› Institutsangaben

Abstract

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Zusammenfassung

Epileptische Anfälle beginnen sehr häufig im Kindesalter, ihre Semiologie kann gerade in dieser Altersklasse sehr variable sein. Die ebenso oft auftretenden altersabhängigen nicht epileptischen paroxysmalen Bewegungsstörungen werden häufig verwechselt. Wir beschreiben in dieser Übersicht das Spektrum der nicht epileptischen altersabhängigen Bewegungsstörungen. Diese zu erkennen ist wichtig, da die Therapie komplett anders gestaltet wird, antiepileptische Medikamente sind kontraindiziert, mit Ausnahme der kinesiogenen Choreoathetose.

Summary

Epileptic seizures very often begin in childhood; their semiology may be quite variable, particularly in this age group. They are frequently confused with age-related, non-epileptic paroxysmal movements, which are just as common. We describe the spectrum of non-epileptic movements in children which it is important to distinguish from epileptic seizures.

Therapeutic measures are completely different for non-epileptic paroxysmal movements, antiepileptic drugs are not necessary except for kinesiogen choreoathetosis.

Schlüsselwörter

Paroxysmale nicht epileptische Bewegungen - epileptische Anfälle

Keywords

Paroxysmal non-epileptic movements - epileptic seizures

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Referenzen

Literatur
1 Afawi Z, Bassan H, Heron S. et al Benign neonatal sleep myoclonus: an autosomal dominant form not allelic to KCNQ2 or KCNQ3.. J Child Neurol 2012 epub
2 Alsaaadi TM, Marquez AV. Psychogenic nonepileptic seizures.. Am Fam Physician 2005; 72: 849-856.
3 Beach R, Reading R. The importance of acknowledging clinical uncertainty in the diagnosis of epilepsy and non-epileptic events.. Arch Dis Child 2005; 90: 1219-1222.
4 Brignole M. and The Task Force on Syncope, European Society of Cardiology. Guidelines on Management (Diagnosis and Treatment) of Syncope - update 2004.. Eur Heart J 2004; 25: 2054-2072.
5 Black JE, Brooks SN, Nishino S. Narcolepsy and syndromes of primary execessive daytime somnolence.. Semin Neurol 2004; 24: 271-282.
6 Bleasel A, Kotagal P. Paroxysmal nonepileptic disorders in children and adolescents.. Semin Neurol 2005; 15: 203-217.
7 Coulter DL, Allen RJ. Benign neonatal sleep myoclonus.. Arch Neurol 1982; 39: 191-192.
8 Deonna T, Martin D. Benign paroxysmal torticollis in infancy.. Arch Dis Child 1981; 56: 956-959.
9 DiMario FJ. Paroxysmal nonepileptic events of childhood.. Semin Pediatr Neurol 2006; 13: 208-221.
10 Echenne B, Rivier F. Benign paroxysmal tonic upward gaze.. Pediatr Neurol 1992; 8: 154-155.
11 Egger J, Grossmann G, Auchterlonie A. Benign sleep myoclonus in infancy mistaken for epilepsy.. BMJ 2003; 326: 975-976.
12 Evans OB. Breath - holding spells.. Pediatr Ann 1997; 26: 312-316.
13 Galvin HK, Newton AW, Vandeven AM. Update on Munchausen syndrome by proxy.. Curr Opin Pediatr 2005; 17: 252-257.
14 Holmes GL, Russman BS. Shuddering attacks.. Am J Dis Child 1986; 140: 72-73.
15 Hüdaoglu O, Dirik E, Yis U, Kurul S. Parental attitude of mothers, iron deficiency anemia, and breath - holding spells.. Pediatr Neurol 2006; 35: 18-20.
16 Kabakus N, Kurt A. Sandifer syndrome: a continuing problem of misdiagnosis.. Pediatr Int 2006; 48: 622-625.
17 Kertesz A. Paroxysmal kinesiogenic choreoathetosis.. Neurol 1967; 17: 680-690.
18 Kostakis A, Manjunatha NP, Kumar A, Moreland ES. Abnormal head posture in a patient with normal ocular motilità: Sandifer syndrome.. J Pediatr Ophthalmol Strabismus 2008; 45: 57-58.
19 Kotagal P, Costa M, Wyllie E, Wolgamuth B. Paroxysmal nonepileptic events in children and adoleycents.. Pediatrics 2002; 110: 46
20 Kuhle S, Tiefenthaler M, Seidl R, Hauser E. Prolonged generalized epileptic seizures triggered by breath-holding spells.. Pediatr Neurol 2000; 23: 271-273.
21 Lehwald N, Krausch M, Franke C. et al Sandifer syndrome - a multidisciplinary diagnostic and therapeutic challenge.. Eur J Pediatr Surg 2007; 17: 203-206.
22 Lempert T. Synkopen.. Nervenarzt 1997; 68: 620-624.
23 Lombroso C, Lerman P. Breath-holding spells (cyanotic and pallid infantile syncope).. Pediatrics 1967; 39: 563-581.
24 McKeon A, Vanghan C, Delanty N. Seizure versus syncope.. Lancet Neurol 2006; 5: 171-180.
25 Maurer VO, Rizzi M, Bianchetti MG, Ramelli GP. Benign neonatal sleep myoclonus: a review oft he literature.. Pediatrics 2010; 125: 919-924.
26 Mocan H, Yildiran A, Orhan F, Erduran E. Breath holding spells in children and respons to treatment with iron.. Arch Dis Child 1999; 81: 261-262.
27 Montagna P. The treatment of restless legs syndrome.. Neurol Sci 2007; 28 (Suppl. 01) (Suppl) S61-S66.
28 Nechay A, Ross LM, Stephenson JB, O’Regan M. Gratification disorder (“infantile masturbation”). A review.. Arch Dis Child 2004; 89: 225-226.
29 Ouvrier RA, Billson F. Benign paroxysmal tonic upgaze of childhood.. J Child Neurol 1988; 3: 177-180.
30 Overeem S, Scammell TE, Jan Lammers G. Hypocretin/ Orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy.. Curr Opin Neurol 2002; 15: 739-745.
31 Paolicchi JM. The spectrum of nonepileptic events in children.. Epilepsia 2002; 43 (Suppl. 03) (Suppl) 60-64.
32 Picchietti D, Allen RP, Walters AS. et al Restlegs legs syndrome: diagnosis, epilemiology, classification and consequences.. Neurol Sci 2007 28. 01 (Suppl) S37-S46.
33 Preblick-Salib C, Jagoda A. Spells. Differential diagnosis and management strategies.. Emerg Med Clin North America 1997; 15: 637-648.
34 Ramelli GP, Sozzo AB, Vella S. et al Benign neonatal sleep myoclonus: an under recognized, non - epileptic condition.. Acta Pediatr 2005; 94: 962-963.
35 Reuber M, Bauer J. Psychogene nichtepileptische Anfälle.. Dtsch Ärztbl 2003; 100: A2013-2018. (Heft 30)
36 Rees MI, Lewis TM, Kwok JB. et al Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB).. Hum Mol Genet 2002; 11: 853-860.
37 Scheepers B, Clouth P, Pickles C. The misdiagnosis of epilepsy: findings of a population study.. Seizure 1998; 7: 403-406.
38 Schreier H. Munchausen by proxy.. Curr Probl Pediatr Adolesc Health Care 2004; 34: 126-143.
39 Somijit S, Lee Y, Berkovic F, Harvey AS. Sandifer syndrome misdiagnosed as refractory partial seizures in an adult.. Epileptic Disord 2004; 6: 49-50.
40 Sun ER, Chen CA, Ho G. et al Iron and the restless legs syndrome.. Sleep 1998; 15: 371-377.
41 Tijssen MA, Vergouwe MN, van Dijk JG. et al Major and minor form of hereditary hyperekplexia.. Mov Dis 2002; 17: 826-830.
42 Uldall P, Alving J, Hansen LK. et al The misdiagnosis of epilepsy in children admitted to a tertiary epilepsy centre with paroxysmal events.. Arch Dis Child 2006; 91: 219-221.
43 Vanasse M, Bedard P, Andermann F. Shuddering attacks in children: an early clinical manifestation of essential tremor.. Neurology 1976; 26: 1027-1030.
44 Vidailhet M. Paroxysmal dyskinesias as a paradigm of paroxysmal movement disorders.. Curr Opin Neurol 2000; 13: 457-462.
45 Yang ML, Fullwood E, Goldstein J, Mink JW. Masturbation in infancy and early childhood presenting as a movement disorder: 12 cases and a review of the literature.. Pediatrics 2005; 116: 1427-1432.
46 Zhou L, Chillag KL, Nigro MA. Hyperekplexia: a treatable neurogenetic disease.. Brain Dev 2002; 24: 669-674.